Aldehyde dehydrogenase (ALDH)

Definition:

Aldehyde dehydrogenase (ALDH) family is cytosolic isoenzyme responsible for oxidizing intracellular aldehydes, thus contributing to the oxidation of retinol to retinoic acid in early stem cell differentiation.Aldehyde dehydrogenase 1 is a tumor stem cell-associated marker in lung cancer.

References:

[1]. Jiang F, et al. Aldehyde dehydrogenase 1 is a tumor stem cell-associated marker in lung cancer. Mol Cancer Res. 2009 Mar;7(3):330-8. [Content Brief]

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