Alpha-2-macroglobulin receptor-associated protein

Definition:

Molecular chaperone for LDL receptor-related proteins that may regulate their ligand binding activity along the secretory pathway.

References:

[1]. Jennifer N Rauch, et al. LRP1 is a master regulator of tau uptake and spread. Nature. 2020 Apr;580(7803):381-385. [Content Brief]

[2]. G Bu, et al. 39 kDa receptor-associated protein is an ER resident protein and molecular chaperone for LDL receptor-related protein. EMBO J. 1995 May 15;14(10):2269-80. [Content Brief]

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