Alveolar capillary dysplasia with misalignment of pulmonary veins

Definition:

Alveolar capillary dysplasia with misalignment of the pulmonary veins (ACD/MPV) is a rare developmental lung disorder of neonates that can cause persistent pulmonary hypertension of the neonate (PPHN). FOXF1 is pathogenic for ACD/MPV and most of the cases have been reported to occur sporadically.

References:

[1]. Naomi B Bishop, et al. Alveolar capillary dysplasia. Am J Respir Crit Care Med. 2011 Jul 15;184(2):172-9. [Content Brief]

[2]. Shih-Pin Hung, et al. Misalignment of lung vessels and alveolar capillary dysplasia: a case report with autopsy. Pediatr Neonatol. 2011 Aug;52(4):232-6. [Content Brief]

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