AMP-activated protein kinase (AMPK)

Definition:

AMP-activated protein kinase (AMPK) is an enzyme which is a highly conserved sensor of low intracellular ATP levels. AMPK is a central mediator of the cellular response to energetic stress and mitochondrial insults and coordinates multiple features of autophagy and mitochondrial biology.

References:

[1]. Herzig S, et al. AMPK: guardian of metabolism and mitochondrial homeostasis. Nat Rev Mol Cell Biol. 2018 Feb;19(2):121-135. [Content Brief]

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