AT-rich interactive domain-containing protein 3B

Definition:

Transcription factor which may be involved in neuroblastoma growth and malignant transformation. Favors nuclear targeting of ARID3A.

References:

[1]. Dongkyoon Kim, et al. REKLES is an ARID3-restricted multifunctional domain. J Biol Chem. 2007 May 25;282(21):15768-77. [Content Brief]

[2]. Kenichiro Kobayashi, et al. ARID3B induces malignant transformation of mouse embryonic fibroblasts and is strongly associated with malignant neuroblastoma. Cancer Res. 2006 Sep 1;66(17):8331-6. [Content Brief]

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