ATP-dependent RNA helicase DDX39A

Definition:

[Isoform 1]: Involved in pre-mRNA splicing. Required for the export of mRNA out of the nucleus.

References:

[1]. Takeyuki Sugiura, et al. DDX39, upregulated in lung squamous cell cancer, displays RNA helicase activities and promotes cancer cell growth. Cancer Biol Ther. 2007 Jun;6(6):957-64. [Content Brief]

[2]. Anne Pryor, et al. Growth-regulated expression and G0-specific turnover of the mRNA that encodes URH49, a mammalian DExH/D box protein that is highly related to the mRNA export protein UAP56. Nucleic Acids Res. 2004 Mar 26;32(6):1857-65. [Content Brief]

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