BEN domain-containing protein 6

Definition:

Acts as a corepressor of recombining binding protein suppressor hairless (RBPJ) and inhibits Notch signaling in neural stem cells, thereby opposing their self-renewal and promoting neurogenesis.

References:

[1]. Qi Dai, et al. BEND6 is a nuclear antagonist of Notch signaling during self-renewal of neural stem cells. Development. 2013 May;140(9):1892-902. [Content Brief]

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