Breast cancer metastasis-suppressor 1-like protein

Definition:

Involved in the histone deacetylase (HDAC1)-dependent transcriptional repression activity. When overexpressed in lung cancer cell line that lacks p53/TP53 expression, inhibits cell growth.

References:

[1]. Anatoly Y Nikolaev, et al. Identification of a novel BRMS1-homologue protein p40 as a component of the mSin3A/p33(ING1b)/HDAC1 deacetylase complex. Biochem Biophys Res Commun. 2004 Oct 29;323(4):1216-22. [Content Brief]

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