C-Maf-inducing protein

Definition:

Plays a role in T-cell signaling pathway. Isoform 2 may play a role in T-helper 2 (Th2) signaling pathway and seems to represent the first proximal signaling protein that links T-cell receptor-mediated signal to the activation of c-Maf Th2 specific factor.

References:

[1]. Philippe Grimbert, et al. The Filamin-A is a partner of Tc-mip, a new adapter protein involved in c-maf-dependent Th2 signaling pathway. Mol Immunol. 2004 Mar;40(17):1257-61. [Content Brief]

[2]. Philippe Grimbert, et al. Truncation of C-mip (Tc-mip), a new proximal signaling protein, induces c-maf Th2 transcription factor and cytoskeleton reorganization. J Exp Med. 2003 Sep 1;198(5):797-807. [Content Brief]

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