CDGSH iron-sulfur domain-containing protein 3, mitochondrial

Definition:

Can transfer its iron-sulfur clusters to the apoferrodoxins FDX1 and FDX2. Contributes to mitochondrial iron homeostasis and in maintaining normal levels of free iron and reactive oxygen species, and thereby contributes to normal mitochondrial function.

References:

[1]. Colin H Lipper, et al. Structure of the human monomeric NEET protein MiNT and its role in regulating iron and reactive oxygen species in cancer cells. Proc Natl Acad Sci U S A. 2018 Jan 9;115(2):272-277. [Content Brief]

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