Centrin-3

Definition:

Plays a fundamental role in microtubule-organizing center structure and function.; As a component of the TREX-2 complex, involved in the export of mRNAs to the cytoplasm through the nuclear pores.

References:

[1]. David Umlauf, et al. The human TREX-2 complex is stably associated with the nuclear pore basket. J Cell Sci. 2013 Jun 15;126(Pt 12):2656-67. [Content Brief]

[2]. Divyang Jani, et al. Functional and structural characterization of the mammalian TREX-2 complex that links transcription with nuclear messenger RNA export. Nucleic Acids Res. 2012 May;40(10):4562-73. [Content Brief]

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