Chronic lymphocytic leukemia (CLL)

Definition:

Chronic lymphocytic leukemia (CLL) is the most common adult leukemia. It is characterized by the clonal expansion of CD⁵⁺ mature B cells in the blood, bone marrow, and lymphoid tissues. CLL is a B cell malignancy characterized by accumulating mature clonal CD5-expressing B cells.

References:

[1]. Kikushige Y. Pathogenesis of chronic lymphocytic leukemia and the development of novel therapeutic strategies. J Clin Exp Hematop. 2020 Dec 15;60(4):146-158. [Content Brief]

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