Clathrin interactor 1

Definition:

Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). May have a role in transport via clathrin-coated vesicles from the trans-Golgi network to endosomes. Stimulates clathrin assembly.

References:

[1]. Christoph Kalthoff, et al. Clint: a novel clathrin-binding ENTH-domain protein at the Golgi. Mol Biol Cell. 2002 Nov;13(11):4060-73. [Content Brief]

[2]. Ian G Mills, et al. EpsinR: an AP1/clathrin interacting protein involved in vesicle trafficking. J Cell Biol. 2003 Jan 20;160(2):213-22. [Content Brief]

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