CMRF35-like molecule 7

Definition:

Acts as an activating immune receptor through its interaction with ITAM-bearing adapter TYROBP, and also independently by recruitment of GRB2.

References:

[1]. Yoshinori Yamanishi, et al. Analysis of mouse LMIR5/CLM-7 as an activating receptor: differential regulation of LMIR5/CLM-7 in mouse versus human cells. Blood. 2008 Jan 15;111(2):688-98. [Content Brief]

[2]. Agueda Martínez-Barriocanal, et al. Molecular and functional characterization of CD300b, a new activating immunoglobulin receptor able to transduce signals through two different pathways. J Immunol. 2006 Sep 1;177(5):2819-30. [Content Brief]

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