Coiled-coil domain-containing protein 14

Definition:

Negatively regulates centriole duplication. Negatively regulates CEP63 and CDK2 centrosomal localization.

References:

[1]. Elif Nur Firat-Karalar, et al. Proximity interactions among centrosome components identify regulators of centriole duplication. Curr Biol. 2014 Mar 17;24(6):664-70. [Content Brief]

[2]. Andrew Kodani, et al. Centriolar satellites assemble centrosomal microcephaly proteins to recruit CDK2 and promote centriole duplication. Elife. 2015 Aug 22;4:e07519. [Content Brief]

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