CXXC-type zinc finger protein 1

Definition:

Transcriptional activator that exhibits a unique DNA binding specificity for CpG unmethylated motifs with a preference for CpGG.

References:

[1]. Chao Xu, et al. The structural basis for selective binding of non-methylated CpG islands by the CFP1 CXXC domain. Nat Commun. 2011;2:227. [Content Brief]

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