Cytosolic 5'-nucleotidase 3A

Definition:

Nucleotidase which shows specific activity towards cytidine monophosphate (CMP) and 7-methylguanosine monophosphate (m(7)GMP). CMP seems to be the preferred substrate.

References:

[1]. Thomas Monecke, et al. Crystal structures of the novel cytosolic 5'-nucleotidase IIIB explain its preference for m7GMP. PLoS One. 2014 Mar 6;9(3):e90915. [Content Brief]

[2]. A Amici, et al. Evidence for essential catalytic determinants for human erythrocyte pyrimidine 5'-nucleotidase. Cell Mol Life Sci. 2005 Jul;62(14):1613-20. [Content Brief]

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