Dengue

Definition:

Dengue is an infectious disease caused by Dengue virus (DENV), a flavivirus in the Flaviviridae family of +ssRNA viruses, and transmitted by Aedes mosquitoes. Dengue is the most prevalent arboviral infection worldwide, and at least four different serotypes of DENV are known causing dengue fever and life-threatening dengue hemorrhagic fever. Dengue is a very old disease with a report of dengue-like illness in China as early as the third century.

References:

[1]. I Kurane, et al. Dengue fever and dengue haemorrhagic fever: challenges of controlling an enemy still at large. Rev Med Virol. 2001 Sep-Oct;11(5):301-11. [Content Brief]

[2]. Jamie Whitehorn, et al. The pathogenesis of dengue. Vaccine. 2011 Sep 23;29(42):7221-8. [Content Brief]

[3]. Scott C Weaver, et al. Molecular evolution of dengue viruses: contributions of phylogenetics to understanding the history and epidemiology of the preeminent arboviral disease. Infect Genet Evol. 2009 Jul;9(4):523-40. [Content Brief]

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