Dipeptidyl aminopeptidase-like protein 6

Definition:

Promotes cell surface expression of the potassium channel KCND2. Modulates the activity and gating characteristics of the potassium channel KCND2. Has no dipeptidyl aminopeptidase activity.

References:

[1]. Heun Soh, et al. I SA channel complexes include four subunits each of DPP6 and Kv4.2. J Biol Chem. 2008 May 30;283(22):15072-7. [Content Brief]

[2]. Henry H Jerng, et al. Modulation of Kv4.2 channel expression and gating by dipeptidyl peptidase 10 (DPP10). Biophys J. 2004 Oct;87(4):2380-96. [Content Brief]

[3]. Edward Seikel, et al. Convergent modulation of Kv4.2 channel alpha subunits by structurally distinct DPPX and KChIP auxiliary subunits. Biochemistry. 2009 Jun 23;48(24):5721-30. [Content Brief]

[4]. Pavel Strop, et al. Structure of a human A-type potassium channel interacting protein DPPX, a member of the dipeptidyl aminopeptidase family. J Mol Biol. 2004 Oct 29;343(4):1055-65. [Content Brief]

[5]. N Yokotani, et al. Non-conservation of a catalytic residue in a dipeptidyl aminopeptidase IV-related protein encoded by a gene on human chromosome 7. Hum Mol Genet. 1993 Jul;2(7):1037-9. [Content Brief]

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