Disco-interacting protein 2 homolog A

Definition:

Catalyzes the de novo synthesis of acetyl-CoA in vitro (By similarity). Promotes acetylation of CTTN, possibly by providing the acetyl donor, ensuring correct dendritic spine morphology and synaptic transmission (By similarity). Binds to follistatin-related protein FSTL1 and may act as a cell surface receptor for FSTL1, contributing to AKT activation and subsequent FSTL1-induced survival and function of endothelial cells and cardiac myocytes.

References:

[1]. Noriyuki Ouchi, et al. DIP2A functions as a FSTL1 receptor. J Biol Chem. 2010 Mar 5;285(10):7127-34. [Content Brief]

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