Divergent protein kinase domain 2A

Definition:

May play a role in cardiomyocyte proliferation through paracrine signaling and activation of the PPI3K-AKT-CDK7 signaling cascade.

References:

[1]. Farideh Beigi, et al. C3orf58, a novel paracrine protein, stimulates cardiomyocyte cell-cycle progression through the PI3K-AKT-CDK7 pathway. Circ Res. 2013 Aug 2;113(4):372-80. [Content Brief]

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