Erythema infectiosum

Definition:

Erythema infectiosum, or fifth disease, is a benign pediatric condition caused by B19 parvovirus. It causes a mild, self-limiting 'slapped-cheek' facial rash with low-grade fever and malaise in immunocompetent children. Parvovirus B 19 also causes a wide range of clinical complications, including thrombocytopenia and neurological manifestations in immunocompromised patients and intrauterine fetal death in primary infected pregnant women.

References:

[1]. E P de Jong, et al. Parvovirus B19 infection in pregnancy: new insights and management. Prenat Diagn. 2011 May;31(5):419-25. [Content Brief]

[2]. K Broliden, et al. Clinical aspects of parvovirus B19 infection. J Intern Med. 2006 Oct;260(4):285-304. [Content Brief]

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