Eukaryotic translation initiation factor 4 gamma 1

Definition:

Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. As a member of the eIF4F complex, required for endoplasmic reticulum stress-induced ATF4 mRNA translation.

References:

[1]. Pauline Adjibade, et al. DDX3 regulates endoplasmic reticulum stress-induced ATF4 expression. Sci Rep. 2017 Oct 23;7(1):13832. [Content Brief]

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