G-protein coupled receptor 78

Definition:

Orphan receptor. Displays a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP.

References:

[1]. Philip G Jones, et al. Tissue distribution and functional analyses of the constitutively active orphan G protein coupled receptors, GPR26 and GPR78. Biochim Biophys Acta. 2007 Jun;1770(6):890-901. [Content Brief]

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