G-protein coupled receptor-associated protein LMBRD2

Definition:

Recruited to ligand-activated beta-2 adrenergic receptor/ADRB2, it negatively regulates the adrenergic receptor signaling pathway. May also regulate other G-protein coupled receptors including type-1 angiotensin II receptor/AGTR1 (Probable).

References:

[1]. Jaeho Paek, et al. Multidimensional Tracking of GPCR Signaling via Peroxidase-Catalyzed Proximity Labeling. Cell. 2017 Apr 6;169(2):338-349.e11. [Content Brief]

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