H/ACA ribonucleoprotein complex non-core subunit NAF1

Definition:

RNA-binding protein required for the maturation of box H/ACA snoRNPs complex and ribosome biogenesis. During assembly of the H/ACA snoRNPs complex, it associates with the complex and disappears during maturation of the complex and is replaced by NOLA1/GAR1 to yield mature H/ACA snoRNPs complex. Probably competes with NOLA1/GAR1 for binding with DKC1/NOLA4.

References:

[1]. Xavier Darzacq, et al. Stepwise RNP assembly at the site of H/ACA RNA transcription in human cells. J Cell Biol. 2006 Apr 24;173(2):207-18. [Content Brief]

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