Hand, foot and mouth disease

Definition:

Hand, foot and mouth disease (HFMD) is a common infection among infants and young children caused by certain enteroviruses in the Picornaviridae family of +ssRNA viruses, such as Coxsackievirus A16 and Enterovirus A71. HFMD is generally a benign febrile exanthematous disease, but complications can occur causing meningitis and encephalitis.

References:

[1]. Kow-Tong Chen, et al. Epidemiologic features of hand-foot-mouth disease and herpangina caused by enterovirus 71 in Taiwan, 1998-2005. Pediatrics. 2007 Aug;120(2):e244-52. [Content Brief]

[2]. Qunying Mao, et al. Coxsackievirus A16: epidemiology, diagnosis, and vaccine. Hum Vaccin Immunother. 2014;10(2):360-7. [Content Brief]

[3]. Tom Solomon, et al. Virology, epidemiology, pathogenesis, and control of enterovirus 71. Lancet Infect Dis. 2010 Nov;10(11):778-90. [Content Brief]

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