Homeobox protein OTX2

Definition:

Transcription factor probably involved in the development of the brain and the sense organs. Can bind to the bicoid/BCD target sequence (BTS): 5'-TCTAATCCC-3'.

References:

[1]. Darya Gorbenko Del Blanco, et al. A novel OTX2 mutation in a patient with combined pituitary hormone deficiency, pituitary malformation, and an underdeveloped left optic nerve. Eur J Endocrinol. 2012 Sep;167(3):441-52. [Content Brief]

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