Human liver microsomes (HLMs)

Definition:

Human liver microsomes contain a wide variety of drug-metabolizing enzymes and are commonly used to support in vitro metabolism studies, such as reaction phenotyping, metabolic stability, metabolite identification (MetID), and enzyme inhibition.

References:

[1]. Asha S, et al. Role of human liver microsomes in in vitro metabolism of drugs-a review. Appl Biochem Biotechnol. 2010 Mar;160(6):1699-722. [Content Brief]

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