Magnesium transporter MRS2 homolog, mitochondrial

Definition:

Magnesium transporter that mediates the influx of magnesium into the mitochondrial matrix. Required for normal expression of the mitochondrial respiratory complex I subunits.

References:

[1]. Martin Piskacek, et al. Conditional knockdown of hMRS2 results in loss of mitochondrial Mg(2+) uptake and cell death. J Cell Mol Med. 2009 Apr;13(4):693-700. [Content Brief]

[2]. G Zsurka, et al. The human mitochondrial Mrs2 protein functionally substitutes for its yeast homologue, a candidate magnesium transporter. Genomics. 2001 Mar 1;72(2):158-68. [Content Brief]

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