Matrix metalloproteases (MMPs)

Definition:

Matrix metalloproteinases (MMPs) are members of an enzyme family that require a zinc ion in their active site for catalytic activity. MMP can catalyze the normal turnover of extracellular matrix (ECM) macromolecules which are critical for maintaining tissue allostasis.

References:

[1]. Charles J Malemud, et al. Matrix metalloproteinases (MMPs) in health and disease: an overview. Front Biosci. 2006 May 1;11:1696-701. [Content Brief]

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