Medium-chain acyl-CoA ligase ACSF2, mitochondrial

Definition:

Acyl-CoA synthases catalyze the initial reaction in fatty acid metabolism, by forming a thioester with CoA. Has some preference toward medium-chain substrates. Plays a role in adipocyte differentiation.

References:

[1]. Ranjan J Perera, et al. Identification of novel PPARgamma target genes in primary human adipocytes. Gene. 2006 Mar 15;369:90-9. [Content Brief]

[2]. Paul A Watkins, et al. Evidence for 26 distinct acyl-coenzyme A synthetase genes in the human genome. J Lipid Res. 2007 Dec;48(12):2736-50. [Content Brief]

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