Methionine-R-sulfoxide reductase B3

Definition:

Catalyzes the reduction of free and protein-bound methionine sulfoxide to methionine. Isoform 2 is essential for hearing.

References:

[1]. Hwa-Young Kim, et al. Methionine sulfoxide reduction in mammals: characterization of methionine-R-sulfoxide reductases. Mol Biol Cell. 2004 Mar;15(3):1055-64. [Content Brief]

[2]. Zubair M Ahmed, et al. Functional null mutations of MSRB3 encoding methionine sulfoxide reductase are associated with human deafness DFNB74. Am J Hum Genet. 2011 Jan 7;88(1):19-29. [Content Brief]

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