Methyltransferase Radiometric Assay

Definition:

Methyltransferase Radiometric Assay is used to study the activity of methyltransferases and the kinetics of methyl transfer reactions. By detecting the transfer of radioactive methyl groups (such as S-adenosylmethionine (SAM)) from the donor to the receptor, this assay quantifies the rate of methylation reactions, widely applied in drug development and epigenetics research.

References:

[1]. Culman J, et al. A radiometric assay for phenylethanolamine N-methyltransferase and catechol O-methyltransferase in a single tissue sample: application to rat hypothalamic nuclei, pineal gland, and heart. Anal Biochem. 1987 Aug 1;164(2):345-54.

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