Mitochondrial folate transporter/carrier

Definition:

Transports folate across the inner membranes of mitochondria. Can also transport FAD across the mitochondrial inner membrane.

References:

[1]. Jimi Kim, et al. Formate rescues neural tube defects caused by mutations in Slc25a32. Proc Natl Acad Sci U S A. 2018 May 1;115(18):4690-4695. [Content Brief]

[2]. András N Spaan, et al. Identification of the human mitochondrial FAD transporter and its potential role in multiple acyl-CoA dehydrogenase deficiency. Mol Genet Metab. 2005 Dec;86(4):441-7. [Content Brief]

[3]. Erin A McCarthy, et al. A mutation inactivating the mitochondrial inner membrane folate transporter creates a glycine requirement for survival of chinese hamster cells. J Biol Chem. 2004 Aug 6;279(32):33829-36. [Content Brief]

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