Mitogen-activated protein kinase kinase kinase kinase 3

Definition:

May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

References:

[1]. K Diener, et al. Activation of the c-Jun N-terminal kinase pathway by a novel protein kinase related to human germinal center kinase. Proc Natl Acad Sci U S A. 1997 Sep 2;94(18):9687-92. [Content Brief]

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