MOB kinase activator 3B

Definition:

Modulates LATS1 expression in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.

References:

[1]. Julia Joung, et al. Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood. Nature. 2017 Aug 17;548(7667):343-346. [Content Brief]

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