mRNA Display Technology

Definition:

mRNA Display Technology involves covalently linking mRNA with the peptide it encodes to form a complex, which is used for high-throughput screening of target proteins that bind to ligands. This technique is widely used in drug screening, protein engineering, and molecular target research.

References:

[1]. Josephson K, et al. mRNA display: from basic principles to macrocycle drug discovery. Drug Discov Today. 2014 Apr;19(4):388-99. [Content Brief]

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