Multimerin-2

Definition:

Inhibits endothelial cells motility and acts as a negative regulator of angiogenesis; it down-regulates KDR activation by binding VEGFA.

References:

[1]. E Lorenzon, et al. MULTIMERIN2 impairs tumor angiogenesis and growth by interfering with VEGF-A/VEGFR2 pathway. Oncogene. 2012 Jun 28;31(26):3136-47. [Content Brief]

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