Necrotizing fasciitis

Definition:

Necrotizing fasciitis (NF) is a severe life-threatening soft tissue infection characterized by rapidly spreading necrosis of the fascia and the subcutaneous tissue. Although more common in adults, NF also affects the pediatric population. Many bacterial organisms can cause NF, but group A Streptococcus is the most common monomicrobial cause of disease. Other bacterial pathogens that have been implicated in NF include Staphylococcus aureus, Clostridium species, and mixed Gram-negative and anaerobic organisms.

References:

[1]. Melanie Burghartz, et al. Complete Genome Sequence of the Urethral Catheter Isolate Myroides sp. A21. Genome Announc. 2015 Mar 5;3(2):e00068-15. [Content Brief]

[2]. N Arif, et al. Deaths from necrotizing fasciitis in the United States, 2003-2013. Epidemiol Infect. 2016 Apr;144(6):1338-44. [Content Brief]

[3]. Nazreen Jamal, et al. Necrotizing fasciitis. Pediatr Emerg Care. 2011 Dec;27(12):1195-9; quiz 1200-2. [Content Brief]

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