Nicotinamide adenine dinucleotide (NAD)

Definition:

Nicotinamide adenine dinucleotide (NAD) is an abundant cofactor. NAD acts as a cosubstrate for several enzymes, such as sirtuins, PARPs and some ectoenzymes like CD38. NAD regulates critical biological processes like gene expression, DNA repair, calcium signalling and circadian rhythms.

References:

[1]. Tannous C, et al. Nicotinamide adenine dinucleotide: Biosynthesis, consumption and therapeutic role in cardiac diseases. Acta Physiol (Oxf). 2021 Mar;231(3):e13551. [Content Brief]

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