NK-tumor recognition protein

Definition:

PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. Component of a putative tumor-recognition complex involved in the function of NK cells.

References:

[1]. S K Anderson, et al. A cyclophilin-related protein involved in the function of natural killer cells. Proc Natl Acad Sci U S A. 1993 Jan 15;90(2):542-6. [Content Brief]

[2]. Tara L Davis, et al. Structural and biochemical characterization of the human cyclophilin family of peptidyl-prolyl isomerases. PLoS Biol. 2010 Jul 27;8(7):e1000439. [Content Brief]

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