Nuclear factor of activated T-cells, cytoplasmic 3

Definition:

Acts as a regulator of transcriptional activation. Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2. Along with NFATC4, involved in embryonic heart development (By similarity).

References:

[1]. Guo-Dong Li, et al. CHP2 activates the calcineurin/nuclear factor of activated T cells signaling pathway and enhances the oncogenic potential of HEK293 cells. J Biol Chem. 2008 Nov 21;283(47):32660-8. [Content Brief]

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