Nuclease Activity Assay

Definition:

Nuclease Activity Assay is a technique used to detect phosphodiester bond hydrolysis in nucleic acids, widely used in studying DNA and RNA degradation mechanisms as well as nuclease substrate specificity and catalytic efficiency.

References:

[1]. Sato S, et al. Highly sensitive nuclease assays based on chemically modified DNA or RNA. Sensors (Basel). 2014 Jul 11;14(7):12437-50. [Content Brief]

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