Ornithine aminotransferase, mitochondrial

Definition:

Catalyzes the reversible interconversion of L-ornithine and 2-oxoglutarate to L-glutamate semialdehyde and L-glutamate.

References:

[1]. Mara Doimo, et al. Functional analysis of missense mutations of OAT, causing gyrate atrophy of choroid and retina. Hum Mutat. 2013 Jan;34(1):229-36. [Content Brief]

[2]. L C Brody, et al. Ornithine delta-aminotransferase mutations in gyrate atrophy. Allelic heterogeneity and functional consequences. J Biol Chem. 1992 Feb 15;267(5):3302-7. [Content Brief]

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