1. Biology Dictionary
  2. Osteogenesis imperfecta

Osteogenesis imperfecta

Definition:

Osteogenesis imperfecta (OI) is characterized by an inherited bone fragility mainly caused by mutations in type I collagen. Poor teeth development, blue sclerae and hearing impairment also manifest in individuals with OI. Mutations in the other genes have been recently identified.

References:

Biomedical Dictionary

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