Postherpetic neuralgia

Definition:

Herpes zoster (HZ) presents as a rash of 2-3 weeks duration in immunocompetent patients that is accompanied by moderate or severe pain. In some patients, pain does not resolve when the rash heals but continues for weeks and, sometimes, for months or years; this phenomenon is known as postherpetic neuralgia (PHN). PHN is the most troublesome side effect associated with HZ.

References:

[1]. Robert H Dworkin, et al. Treatment and prevention of postherpetic neuralgia. Clin Infect Dis. 2003 Apr 1;36(7):877-82. [Content Brief]

[2]. Young Hoon Jeon, et al. Herpes Zoster and Postherpetic Neuralgia: Practical Consideration for Prevention and Treatment. Korean J Pain. 2015 Jul;28(3):177-84. [Content Brief]

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