Primary failure of tooth eruption

Definition:

Primary failure of tooth eruption (PFE) is a condition in which tooth retention occurs without mechanical interference. Defects in PTHR1 are the cause of PFE.

References:

[1]. Eva Decker, et al. PTHR1 loss-of-function mutations in familial, nonsyndromic primary failure of tooth eruption. Am J Hum Genet. 2008 Dec;83(6):781-6. [Content Brief]

[2]. Sofia Ahmad, et al. The clinical features and aetiological basis of primary eruption failure. Eur J Orthod. 2006 Dec;28(6):535-40. [Content Brief]

[3]. W R Proffit, et al. Mechanism and control of tooth eruption: overview and clinical implications. Orthod Craniofac Res. 2009 May;12(2):59-66. [Content Brief]

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