Protein phosphatase 1L

Definition:

Acts as a suppressor of the SAPK signaling pathways by associating with and dephosphorylating MAP3K7/TAK1 and MAP3K5, and by attenuating the association between MAP3K7/TAK1 and MAP2K4 or MAP2K6.

References:

[1]. Jun-ichi Saito, et al. Regulation of apoptosis signal-regulating kinase 1 by protein phosphatase 2Cepsilon. Biochem J. 2007 Aug 1;405(3):591-6. [Content Brief]

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