Protein transport protein Sec61 subunit gamma

Definition:

Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across endoplasmic reticulum (ER) (By similarity). Component of a ribosome-associated ER translocon complex involved in multi-pass membrane protein transport into the ER membrane and biogenesis. The SEC61 channel cooperates with the translocating protein TRAM1 to import nascent proteins into the ER (By similarity).

References:

[1]. Philip T McGilvray, et al. An ER translocon for multi-pass membrane protein biogenesis. Elife. 2020 Aug 21;9:e56889. [Content Brief]

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